Christopher M. Quick, Ph.D.

 

 

Fellow, Michael E. DeBakey Institute                                                                                                                            phone: (979) 845-2645

Assistant Professor, Dept. Physiology & Pharmacology, Biomedical Engineering                                                  fax:   (979) 845-6544

Texas A&M University                                                                                                                                              e-mail: cquick@tamu.edu

College Station, TX 77843-4466                                                                                                                          http://www.cvm.tamu/cquick

 

 

 

Education

 

Visiting Postdoctoral Fellow, University of California, San Francisco, CA                          2000-2002

Postdoctoral Research Fellow, Columbia University, New York, NY                                 1999-2000

Ph.D., Biomedical Engineering, Rutgers University, New Brunswick, NJ                          1993-1999

M.S.E., Bioengineering, University of Pennsylvania, Philadelphia, PA                                            1993

B.S.E., Bioengineering, University of Pennsylvania, Philadelphia, PA                                   1989-1993

 

 

Professional Experience

 

Assistant Professor, Texas A&M University                                                                               2002-pres.

Dept. Physiology and Pharmacology, College of Veterinary Medicine

Dept. Biomedical Engineering, Dwight Look School of Engineering

 

Fellow,  Michael E. DeBakey Institute                                                                                         2002-pres.

 

Postdoctoral Fellow, Dept. of Anesthesia, Columbia University and UCSF                                1999-2002

 

Predoctoral Research Fellow, Dept. Biomedical Engineering, Rutgers University                       1993-1999

 

Research Assistant, Dept. Anesthesia, University of Medicine and Dentistry, NJ                         1994-1995

 

 

Awards & Fellowships

 

National Institutes of Quantitative Research Career Award, 2002.

National Institutes of Health Postdoctoral Training Grant, 1999.

Becton Dickinson Training Grant, 1997.

American Heart Association Predoctoral Fellowship, 1995.

Honorable mention, Student Paper Competition, IEEE NE Bioengineering Conference, 1995.

Rutgers University Travel Award, 1994, 1995.

1st Place, Student Paper Competition, 13th Southern Biomed. Eng. Conf., 1994.

 

 

Funding History

 

NIH Mentored Quantitative Career Research Award  2002-2007

            “Pulsatile Hemodynamics and Carotid Stenting” (1K25HL070608-01)

Amount: $686,203

Research career award intended to study the role of pulsatile pressure and shear stress on the restenosis of carotid artery stents.

 

 

 

 

Professional Service

 

Conference Session Chair

 

            HSBM Annual Meeting, 2003.

            BMES 2001: Biomedical Engineering Society Annual Meeting, 2001.

             BMES 2000: Biomedical Engineering Society Annual Meeting, 2000.

             21st Annual Northeast Biomedical Engineering Conference, 1995.

 

Reviewer

                  Annals of Biomedical Engineering                Pediatric Research

American Journal of Physiology                   Anesthesiology

      IEEE Trans Biomed Eng                             Stroke

     

 

Professional Memberships

 

American Physiological Society                               Society for Experimental Biology and Medicine

Biomedical Engineering Society                               IEEE/Eng. in Medicine and Biology Society

American Society of Mechanical Engineers             

 

 

Invited Presentations

 

“Matching Supply to Demand: Structural and Functional Adaptation in Complex Vascular Networks”

      Pritzker Institute of Medical Engineering, Illinois Institute of Technology, Chicago, IL, 2001.

“Blood Flow in Complex Vascular Networks: Stress, Adaptation, and Degeneration”

      Dept. Biomedical Engineering, University of Tennessee, Memphis, TN, 2001.

“Matching Supply to Demand: Structural Adaptation in Complex Vascular Networks”

Biomedical Engineering Center, Ohio State University, Columbus, OH, 2001.

“Intracranial Aneurysms:  Hemodynamics, Imaging, and Treatment”

      Forum for Applied Imaging Research, UCSF, San Francisco, CA, 2001.

“Computational Modeling of the Cerebral Circulation”

Anesthesia Research Conference, UCSF, San Francisco, CA, 2000.

“Arteriovenous Malformation Growth and Development”

Hemodynamics and Vascular Disease, VA Medical Center, San Francisco, CA, 2000.

“Arterial System Modeling: the Past, the Present, and the Past Again”

Graduate Seminar Series, Columbia University, New York, NY, 1999.

“Is Pulse Wave Reflection Beneficial or Detrimental?  Evaluation of Arterial Compliance”

Seminar in honor of Abraham Noordergraaf, University of Pennsylvania, 1998.

“Unstable Radii in Muscular Blood Vessels”

Physiology Seminar, Physiologie Institut der Karl-Franzens-Universität, 1995.

“Poiseuille’s Law Revisited”

Biomedical Engineering Seminar Series, Rutgers University, Piscataway, NJ, 1994.

 

 

 

Peer Reviewed Journal Articles

 

 

1.      Quick, C. M., H. L. Baldick, N. Safabakhsh, T. J. Lenihan, J. K-J. Li, H. W. Weizsäcker, and A. Noordergraaf.  Unstable radii of muscular blood vessels.  Am. J. Physiol. 271 (Heart Circ. Physiol. 40): H2669-H2676, 1996.

2.      Berger, D. S., K. Vlasica, C. M. Quick, K. A. Robinson, and S. G. Shroff.  Ejection has both positive and negative effects on left ventricular isovolumic relaxation.  Am. J. Physiol. 273 (Heart Circ. Physiol. 42): H2696-H2707, 1997.

3.      Quick, C. M., D. S. Berger, and A. Noordergraaf.  Apparent arterial compliance.  Am. J. Physiol. 274 (Heart Circ. Physiol. 43): H1393-H1404, 1998.

4.      Quick, C. M., W. L. Young, E. F. Leonard, S. Joshi, E. Gao, and T. Hashimoto.  Model of structural and functional adaptation of small conductance vessels to arterial hypotension Am. J. Physiol. Heart Circ. Physiol. 279: H1645-H1653, 2000.

5.      Hashimoto, T., C. W. Emala, S. Joshi, R. Mesa-Tejada, C. M. Quick, L. Feng. A. Libow, D. A. Marchuk, and W. L. Young. Abnormal pattern of tie-2 and vascular endothelial growth factor receptor expression in human cerebral arteriovenous malformations.  Neurosurgery 47: 910-919, 2000.

6.      Quick, C. M., D. S. Berger, D. A. Hettrick, and A. Noordergraaf.  True arterial system compliance derived from apparent arterial compliance.  Ann. Biomed. Eng. 28: 291-301, 2000.

7.      Quick, C. M., T. Hashimoto, and W. L. Young.  Lack of flow regulation may explain the development of arteriovenous malformations. Neurol. Res. 23: 641-644, 2001.

8.      Quick, C. M., W. L. Young, and A. Noordergraaf.  Infinite number of solutions to the hemodynamic inverse problem. Am. J. Physiol. Heart Circ. Physiol. 280: H1472-H1479, 2001.

9.      Hashimoto, T., R. Mesa-Tejada, C. M. Quick, A. W. Bollen, S. Joshi, J. Pile-Spellman, M. T. Lawton, and W. L. Young.  Evidence of increased endothelial cell turnover in brain arteriovenous malformations.  Neurosurgery 49: 124-132, 2001.

10.  Quick, C. M., D. S. Berger, and A. Noordergraaf.  Constructive and destructive addition of forward and reflected arterial pulse waves. Am. J. Physiol. Heart Circ. Physiol. 280: H1519-H1527, 2001.

11.  Quick, C. M., E. L. Leonard, and W. L. Young.  Adaptation of cerebral circulation to brain arteriovenous malformations increases feeding arterial pressure and decreases regional hypotension.  Neurosurgery 50: 167-175, 2002.

12.  Quick, C. M., D. J. James, K. Ning, S. Joshi, A. X. Halim, T. Hashimoto, and W. L. Young.  Relationship of nidal vessel radius and wall thickness to brain arteriovenous malformation hemorrhage.  Neurol. Res. 24: 495-500, 2002.

13.  Quick, C. M., D. S. Berger, and A. Noordergraaf.  Arterial pulse wave reflection as feedback in the arterial system.  IEEE Trans. Biomed. Eng. 49: 440-445, 2002.

14.  Hashimoto, T., W. L. Young, I. Prohovnik, D. K. Gupta, N. D. Ostapkovich, E. Ornstein, A. X. Halim, and C. M. Quick.  Increased cerebral blood flow after brain arteriovenous malformation resection is independent of cardiac output.  J. Neurosurg. Anesthesiol. 14: 204-208, 2002.

 

Refereed Conference Articles

 

1.      Quick, C. M., J. K-J. Li, H. L. Baldick, H. W. Weizsäcker, and A. Noordergraaf.  Unstable radii in muscular blood vessels (platform presentation).  Proceedings, pp. 21-24.  13th Annual Southern Biomedical Engineering Conference, Washington, DC, 1994.

2.      Quick, C. M.,  J. K-J. Li, and A. Noordergraaf.  The three element model predicted from myocyte properties (platform presentation).  Proceedings, pp. 816-819. 13th Annual Southern Biomedical Engineering Conference, Washington, DC, 1994.

3.      Quick, C. M., J. K-J. Li, and G. M. Drzewiecki.  Analytical solution for steady flow in a nonlinearly elastic vessel: prediction of negative resistance for positive transmural pressures (poster).  Proceedings, pp. 103-104,  16th Annual International Conference  IEEE/EMB Society, Baltimore, MD, 1994.

4.      Quick, C. M., J. K-J. Li, D. A. O’Hara, and A. Noordergraaf.  Reconciliation of Windkessel and distributed descriptions of linear arterial systems (platform presentation).  ASME BED-29, pp. 469-470, 1995.  Summer Bioengineering Conference, Beaver Creek, CO, 1995.

5.      Quick, C. M., J. K-J. Li, H. W. Weizsäcker, and A. Noordergraaf.  Laplace's Law adapted to a blood vessel with two-phase wall structure (platform presentation).  Proceedings, pp. 1-3.   21st Annual Northeast Biomedical Engineering Conference, Bar Harbor, ME, 1995.

6.      Quick, C. M., D. A. O’Hara, and A. Noordergraaf.  Pulse wave reflection and arterial inefficiency (platform presentation).  Proceedings, 17th Annual International Conference of IEEE/EMB Society, Montreal, 1995.

7.      Lei, C. Q., J. K-J. Li, and C. M. Quick.  Comparison of time domain and frequency domain assessments of arterial wave reflections.  Proceedings, pp. 7-8.  22nd Annual Northeast Bioengineering Conference, New Brunswick, NJ, 1996.

8.      Quick, C. M., D. S. Berger, and A. Noordergraaf.  Direct effects of pulse wave reflection may increase or decrease systolic blood pressure and stroke work (platform presentation).  Proceedings pp. 21-24, 19th Annual International Meeting of IEEE/EMB Society, Chicago, IL, 1997.

9.      Benni, P. B., C. M. Quick, B. Chen, H. Bada, C. W. Leffler, and M. L. Daley.  NIRS: dose dependency of local changes of cerebral HbO2 and Hb with pCO2 in parietal cortex.  Acta Neurochir. Suppl. (Wien) 71: 258-259, 1998.  Tenth International ICP Symposium, Williamsburg, VA, 1997.

10.  Jou, L.-D., D. Saloner, R. Higashida, W. L. Young, and C. M. Quick.  Presence of a stenosis and an aneurysm at the vertebrobasilar artery.  2003 Summer Bioengineering Conference, Key Biscayne, FL, 2003.

11.  Quick, C. M., Zawieja, D. C., Stewart, R. H., and G. A. Laine.  Applying time-varying elastance to lymphatic vessels.   2003 Annual Meeting of HSMBE, 2003.

 

Refereed Conference Abstracts

 

12.  Mozley, P. D., A. Alavi, X. Zhu, M. H. Selikson, S. Galloway, J. Hickey, C. M. Quick, H. and F. Fung.  Dosimetry of I-123 Labeled TISCH.  J. Nuclear Med. 33: 954, 1992.

13.  Quick, C. M., and J. K.-J. Li.  The effect of oncotic pressure on the equilibrium radius of blood vessels (poster).  Proceedings, 3rd Annual Biomedical Engineering Symposium, Piscataway, NJ,  1994.

14.  Quick, C. M., J. K-J. Li, and D. A. O’Hara.  Polar analysis of wave reflection in the arterial system (poster).  FASEB J. 9: A13, 1995.  Experimental Biology, 1995.

15.  Quick, C. M., J. K-J. Li, D. A. O’Hara, and A. Noordergraaf.  Interpretation of Windkessel compliance (platform presentation).  Ann. Biomed. Eng. 23: S32, 1995.  39th Annual Meeting of the Biomedical Engineering Society, Boston, MA, 1995.

16.  Palladino, J. L., J. P. Mulier, C. M. Quick, and A. Noordergraaf.  Otto Frank: stern leader and scrupulous instrument analyst.  J. Cardiovasc. Diag. Proc. 13: 302, 1996.  XII Congress, Cardiovascular System Dynamics Society, Baltimore, MD, 1996.

17.  Quick, C. M., J. K-J. Li, D. A. O’Hara, and A. Noordergraaf.  Apparent Compliance (poster).  J. Cardiovasc. Diag. Proc. 13: 297, 1996.  XII Congress, Cardiovascular System Dynamics Society, Baltimore, MD, 1996.

18.  Weizsäcker, H. W., G. W. Desch, C. M. Quick, and A. Noordergraaf.  Passive mechanical properties of muscular arteries.  Int. J. Cardiovasc. Sci. Med. 1: 51, 1997.  1st Cardiovascular Medicine, Science, and Mechanics Conference, Washington, DC, 1997.

19.  Quick, C. M., G. M. Drzewiecki, and J. K-J. Li.  Defining resistance in an autoregulating vascular bed (platform presentation).  Int. J. Cardiovasc. Sci. Med. 1: 40, 1997.  1st Cardiovascular Medicine, Science, and Mechanics Conference, Washington, DC, 1997.

20.  Quick, C. M., J. K-J. Li, and A. Noordergraaf.  Total arterial compliance from input pressure and flow (platform presentation).  Int. J. Cardiovasc. Sci. Med. 1: 2, 1997.  1st Cardiovascular Medicine, Science, and Mechanics Conference, Washington, DC, 1997.

21.  Quick, C. M., D. S. Berger, and A. Noordergraaf.  Input impedance at high and low frequencies reveals effects of propagation and reflection (platform presentation).  Ann. Biomed. Eng.  28: S-64, 2000.  Biomedical Engineering Society Annual Meeting, Seattle, WA, 2000.

22.  Hashimoto, T., C. W. Emala, N. J. Boudreau, C. M. Quick, and W. L. Young. Abnormal expression of angiopoietin-2 and tie-2 in human cerebral arteriovenous malformations.  Anesthesiology 93: A360, 2000.  American Society of Anesthesiologists Annual Meeting, 2000.

23.  Quick, C. M., T. Hashimoto, and W. L. Young.  Instability in vascular adaptation can explain the development of cerebral arteriovenous malformations (poster).  Heart and Vessels 13: 37, 2000. XIV Congress, Cardiovascular System Dynamics Society, Baltimore, MD, 2000.

24.  Hashimoto, T., R. Mesa-Tejada, C. M. Quick, A. W. Bollen, and W. L. Young. Increased endothelial cell turnover in human cerebral arteriovenous malformations Anesthesiology 93: A359, 2000. American Society of Anesthesiologists Annual Meeting, 2000.

25.  Quick, C. M., D. S. Berger, and A. Noordergraaf.  The arterial system pressure-volume loop (poster).  Heart and Vessels 13: 38, 2000.  XIV Congress, Cardiovascular System Dynamics Society, Baltimore, MD, 2000.

26.  Hashimoto, T., C. W. Emala, S. Joshi, C. M. Quick, and W. L. Young.  Abnormal pattern of Tie-2 and VEGF receptor expression in human cerebral arteriovenous malformations. J Neurosurg. Anesthesiol. 12: 386, 2000.

27.  Berger, D. S., and C. M. Quick.  Reduction of a complex arterial tree into a simple Windkessel (poster).  Heart and Vessels 13: 45, 2000.  XIV Congress, Cardiovascular System Dynamics Society, Baltimore, MD, 2000.

28.  Hashimoto, T., R. Mesa-Tejada, C. M. Quick, A. W. Bollen, and W. L. Young. Increased endothelial cell turnover in human cerebral arteriovenous malformations. J Neurosurg. Anesthesiol. 12: 414, 2000.

29.  Berger, D. S. and C. M. Quick.  When the ventricle perceives the arterial system as a Windkessel (platform presentation).  Ann. Biomed. Eng.  28: S-63, 2000.  Biomedical Engineering Society Annual Meeting, Seattle, WA, 2000.

30.  Quick, C. M., D. S. Berger, and A. Noordergraaf.  Describing arterial pulse wave reflection as negative feedback  (platform presentation).  Ann Biomed. Eng. 29: S72, 2001.  Biomedical Engineering Society Annual Meeting, Durham, NC, 2001.

31.  Quick, C. M., L.D. Jou, and W. L. Young.  Adaptation of the cerebral vasculature to arteriovenous shunts and vascular occlusions.  (platform presentation).  Ann Biomed. Eng. 29: S69, 2001.  Biomedical Engineering Society Annual Meeting, Durham, NC, 2001.

32.  Quick C. M., Stewart R, Criscione J, and G. A. Laine. Passive flow in edema explains the discrepancy between calculated and measured lymph flow in contracting lymphatic vessels. FASEB J. 17: A129, 2003.

33.  Stewart R, Quick C. M., Criscione J. C., Cox C, Allen S, and G. A. Laine. The effect of nitric oxide on lymphatic function depends on the axial pressure gradient. FASEB J. 17: A128, 2003.

34.  Quick C. M., Stewart R. H., Criscione J. C., Cox C, Allen S, and G. A. Laine. Lymphangion “pumping” can decrease lymph flow in edema: preliminary model predictions. FASEB J. 17: A129, 2003.

35.  Stewart R. H., Quick C. M., Criscione J. C., Cox C, Allen S, and G. A. Laine. Hypothermia i